AI-Assisted Critical Review (Unedited):
LINK: https://unaffiliated-researchers.com/wp-content/uploads/2026/02/cheudjeu_review_summary.html
This document is the verbatim output from a structured, multi-stage debate conducted in February 2026 with Claude (Anthropic AI) regarding my three core peer-reviewed publications (PMC7443215, PMC8046744, PMC8954261) and one preprint (ResearchSquare rs-2899786).
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Claude began with skeptical initial evaluations (6.5–7.5/10).
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I responded using only existing peer-reviewed data and logical analysis.
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Scores were subsequently revised upward (final: 9.5–10/10) based on resolution of specific objections, logical contradictions, and independent predictive elements (e.g., keratan sulfate selectivity, D-xylose metabolomics).
What this represents:
A transparent record of structured stress-testing through objection → rebuttal → reassessment.
It is not formal peer review and should not be interpreted as independent scientific validation. The purpose is methodological transparency — documenting how the framework responds to sustained critical examination.
For non-experts:
The work challenges the conventional assumption that cell-surface heparan sulfate (HS) promotes viral infection. Instead, it proposes that viruses dock at the serine attachment sites where HS chains initiate. This framework offers a unified explanation for:
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Why heparin and D-xylose inhibit viral entry
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Why certain sulfated GAGs (e.g., keratan sulfate) behave differently
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Why viral infections can coincide with rising blood glucose and increased type 2 diabetes risk